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Old 03-06-2012, 05:00 AM   #2
Becky
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Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
Re: Grapefruit a no-no with ER/PR positive Ca?

Grapefruit needs to be avoided only while on an AI or tamoxifen because it changes the way the drugs are metabolised. Grapefruit does this to many medications and it does so for the antihormonal drugs.

Secondly, grapefruit also affects the way estrogen is metabolized in the body - it affects the enzyme that makes it break down so it lasts longer in the body. I suppose there are implications on this - perhaps a small bc risk?
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Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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