[Lida]

Dear Carolyn,
I know what is like to be tolerating a chemo and almost forget about "the deep valleys". I was tolerating Herceptin/Taxatere/Carboplatin pretty well, but had major progression in my 5th month (after good tumor markers a month before progression!). I just started Herceptin/Ixempra; that may be an option for you. Also Doxil/Herceptin was suggested by my onc and seemed to be pretty effective in a small study, which also said adding those 2 is not as cardio risky as they thought -average decrease in Left ejection was 4 percent. But, I still wanted to wait with that one. The Herceptin/Taxatere/Carboplatin is a good synergistic combinaton and it helped me though I had already had Taxatere and other Taxanes, so maybe it is another option. Yes, the t-dm1 seems promising, and I wish I could get it now, also! Lets keep plugging away, Lida