my onc. ( in Seattle where all the trials were, so she is pretty well informed) said that there was not any "data" on herceptin without chemo. I had invasive lobular, small tumor-8mm, bilateral mastectomy, nodes neg, ER+,PR+,Her2+ (fish score 2.94...not high but over the 'limit'). So I opted for 6 rounds of A/C...got very sick after 2nd round, so only did 4 treatments. I have now started on herceptin every 3 weeks, and arimidex for the ER+. I think that she might have done the herceptin without the chemo, then I had an Oncotype DX test, which showed a 'high intermediate'risk of recurrence within 10 years, so we went with the chemo, and herceptin. I am going to hit this with all the big guns available!!!
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