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Old 10-29-2017, 12:00 AM   #4
Pamelamary
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Join Date: Apr 2012
Location: Melbourne, Australia
Posts: 494
Re: Any good chemos I could try?

Hi Amy,
What about trials of the new Her2+ drugs - Margetuxumab and tucatinib? I know they are both being trialled here in Australia, but little else as I am still relying on Vitamin H. As far as I know, immunotherapy drugs like keytruda haven't been the magic bullets for MBC. Also, as I think you are Er+, any of the new ones appropriate?
Quiz your oncologist. Will have all digits crossed for you.
Best wishes..... Pam
__________________
Diagnosed 2004: Lumpectomy - 2 tumours, both grade 1 infiltrating duct carcinoma, about 12mm. ER+,
C-erbB-2 status 3+.
Clear margins, no nodal involvement.
Radiotherapy, i year Tamoxifen, 4 years Arimidex.
Rediagnosed 2012: Multiple bone metastases.
3/12: began on Marianne trial - T-DM1 + Pertuzamab/Placebo.
5/12:Unexpected development of numerous bilateral liver mets. Came off trial.
Started Docetaxol/ Herceptin + Zometa.
8/12:Bones stable +major regression in liver (!)
9/12:Can't take any more Docetaxol! Start on Herceptin and Tamoxifen. Cross fingers!
Changed to Denosumab.
11/12: Scan shows stable - yay!
11/13: Still stable :-) !!!
1/16: All stable, but lowered calcium, so switched to Zometa 3 monthly.
2/19: Happily still stable on Herceptin, Letrozole and 3 monthly Zometa.
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