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Old 01-03-2019, 10:06 PM   #1
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Research illuminates abilities of ADAR1 to ‘hyper-mutate’ tumor suppressor RNAs in le

Writing in the January 3 issue of Cancer Cell, researchers at University of California San Diego School of Medicine report that detection of "copy editing" by a stem cell enzyme called ADAR1, which is active in more than 20 tumor types, may provide a kind of molecular radar for early detection of malignancies and represent a new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.

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