The arguments as to health issues surrounding fructose and its metabolism are complex.
Sucrose, table sugar is made of equal amounts of fructose and glucose.
It is pretty clear that refined fructose as HFCS or table sugar as part of a diet that exceeds the body's energy requirements is certainly a negative health factor.
Arguably refined foods generally are not optimal for health because they have been stripped of nutrients, which makes refined sweeteners a no no.
In comparison fructose in fruit comes with a whole range of protective nutrients, and as a species we have been eating it in varying quantities for a very long time. This leaves the question how much fruit and what sort is optimal to general health, and for particular conditions such as cancer.
http://www.theglobeandmail.com/life/...rticle1316253/
"However, the data showed that cancer cells used fructose and glucose in very different ways, even though they are structurally similar. Compared to glucose, fructose was a potent activator of a key cellular pathway that drives cancer cell division.
Not only did cancer cells prefer fructose, the sugar also triggered cellular activities that enabled malignant cells to use both glucose and fructose more rapidly."