[RobinP]

If Herceptin down regulates gama PPAR, as suggested by the first few article posts in this thread, then dietary supplements that downregulate the her2pathway would also decrease gama PPAR, such as green tea, GLA, ALA, DHA and EPA. It would appear that these natural inhibitors of gama PPAR would help block the her2 pathway. Of course, perhaps the beneficial alpha PPAR would be beneficial too. If so, perhaps natural supplements increasing alpha PPAR would have efficacy.