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Old 10-13-2019, 02:47 AM   #2
R.B.
Senior Member
 
Join Date: Mar 2006
Posts: 1,843
Re: Cannabinoid receptors – main ligands are Omega 3 and 6 derivatives, not hemp prod

This is a useful summary from Harvard Health

These products may well have significant uses but there is still a lot we do not know.

Might concentrated Omega 3 endocannabinoids do the same things - for me it is likely they would in terms of pain etc - hopefully one day somebody will do the necessary research.



https://www.health.harvard.edu/blog/...-2018082414476

Cannabidiol (CBD) — what we know and what we don’t
Posted August 24, 2018, 6:30 am , Updated August 27, 2019, 5:21 pm
Peter Grinspoon, MD
Peter Grinspoon, MD
Contributor


Is cannabidiol safe?

"Side effects of CBD include nausea, fatigue and irritability. CBD can increase the level in your blood of the blood thinner coumadin, and it can raise levels of certain other medications in your blood by the exact same mechanism that grapefruit juice does. A significant safety concern with CBD is that it is primarily marketed and sold as a supplement, not a medication. Currently, the FDA does not regulate the safety and purity of dietary supplements. So you cannot know for sure that the product you buy has active ingredients at the dose listed on the label. In addition, the product may contain other (unknown) elements. We also don’t know the most effective therapeutic dose of CBD for any particular medical condition."


"The bottom line on cannabidiol

Some CBD manufacturers have come under government scrutiny for wild, indefensible claims, such that CBD is a cure-all for cancer, which it is not. We need more research but CBD may be prove to be an option for managing anxiety, insomnia, and chronic pain. Without sufficient high-quality evidence in human studies we can’t pinpoint effective doses, and because CBD is currently is mostly available as an unregulated supplement, it’s difficult to know exactly what you are getting. If you decide to try CBD, talk with your doctor — if for no other reason than to make sure it won’t affect other medications you are taking."
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