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R.B. · 11-01-2013, 02:33 PM

A paper looking at development and intelligence in areas including of modest fluoride in water and low iodine.

There is no wider detail as to diet or mineral intake, so much we do not know in terms of potential relevance and comparability to Europe and America.

None the less the paper does indicate potential serious effects on development where fluoride intake is modest and iodine intake low, whcih in light of the figures above as to the iodine status of adolescent and pregnant females in the UK is scary in its possible implications.

http://www.slweb.org/IDD.html

Discussion

One hundred and four children with mental retardation were detected in all. Area A had 25%, area B 16%, and area C 8%. The significant differences in IQ among these regions suggests that fluoride can exacerbate central nervous lesions and somatic developmental disturbance caused by iodine deficiency. This may be in keeping with fluoride's known ability to cause degenerative changes in central nervous system cells and to inhibit the activities of many enzymes, including choline enzymes, causing disturbance of the nerve impulse (5). We found significant differences among the three areas, indicating that lack of iodine in children results in disturbance of the process of growth and ossification and that high fluoride intake can further disturb bone development (6,7). Also, the auditory threshold was significantly different among the three areas, with severe loss of hearing in high fluoride and low iodine areas. Severe iodine deficiency in early fetal life has adverse effects on the development and differentiation of the acoustic organ, and we suggest that high fluoride intake may also promote hearing loss. . . MORE

Summary

We studied a total of 769 schoolchildren of 7-14 years in three areas, characterized by intakes of (A) low iodine, high fluoride; (B) low iodine, normal fluoride; and (C) iodine supplemented, normal fluoride. Results for the following parameters for areas A, B, and C, respectively were: (a) average IQ: 71, 77, 96; (b) average auditory threshold (in dB): 24, 20, 16; (c) bone age retardation (%): 28, 13, 4; (d) thyroid 131I uptake (%): 60, 50, 24; and (e) serum TSH (mU/ml): 21, 11, 6. Statistically significant differences existed between these areas, suggesting that a low iodine intake coupled with high fluoride intake exacerbates the central nervous lesions and the somatic developmental disturbance of iodine deficiency. The detection rate of subclinical endemic cretinism in children with mental retardation was 69%, and the total attack rate of subclinical endemic cretinism 9%.

11-01-2013, 02:33 PM	#58
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo A paper looking at development and intelligence in areas including of modest fluoride in water and low iodine. There is no wider detail as to diet or mineral intake, so much we do not know in terms of potential relevance and comparability to Europe and America. None the less the paper does indicate potential serious effects on development where fluoride intake is modest and iodine intake low, whcih in light of the figures above as to the iodine status of adolescent and pregnant females in the UK is scary in its possible implications. http://www.slweb.org/IDD.html Discussion One hundred and four children with mental retardation were detected in all. Area A had 25%, area B 16%, and area C 8%. The significant differences in IQ among these regions suggests that fluoride can exacerbate central nervous lesions and somatic developmental disturbance caused by iodine deficiency. This may be in keeping with fluoride's known ability to cause degenerative changes in central nervous system cells and to inhibit the activities of many enzymes, including choline enzymes, causing disturbance of the nerve impulse (5). We found significant differences among the three areas, indicating that lack of iodine in children results in disturbance of the process of growth and ossification and that high fluoride intake can further disturb bone development (6,7). Also, the auditory threshold was significantly different among the three areas, with severe loss of hearing in high fluoride and low iodine areas. Severe iodine deficiency in early fetal life has adverse effects on the development and differentiation of the acoustic organ, and we suggest that high fluoride intake may also promote hearing loss. . . MORE Summary We studied a total of 769 schoolchildren of 7-14 years in three areas, characterized by intakes of (A) low iodine, high fluoride; (B) low iodine, normal fluoride; and (C) iodine supplemented, normal fluoride. Results for the following parameters for areas A, B, and C, respectively were: (a) average IQ: 71, 77, 96; (b) average auditory threshold (in dB): 24, 20, 16; (c) bone age retardation (%): 28, 13, 4; (d) thyroid 131I uptake (%): 60, 50, 24; and (e) serum TSH (mU/ml): 21, 11, 6. Statistically significant differences existed between these areas, suggesting that a low iodine intake coupled with high fluoride intake exacerbates the central nervous lesions and the somatic developmental disturbance of iodine deficiency. The detection rate of subclinical endemic cretinism in children with mental retardation was 69%, and the total attack rate of subclinical endemic cretinism 9%. Last edited by R.B.; 11-01-2013 at 04:24 PM..