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Old 08-05-2011, 10:08 AM   #3
KristinSchwick
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Join Date: Jun 2011
Location: Iowa
Posts: 231
Re: About to start the Tykerb/Xeloda combo tips please

This has been a wonderful combination for me, my cancer antigens decreased ALOT. However you can't inhibit human epidermal growth factor (HER) 1,2 without causing some annoying side effects (so says my doc). First and foremost, stock up on anti-diahrrea pills and always have some on you. Second, track the foods that you eat, esp dairy and salads- they tend to aggrevate the diahrrea. I switched to soy milk and the diahrrea is so much reduced. If it seams unbearable, think BRAT- bananas, rice, applesauce and toast. Also and this I wish I knew ahead of time, during the days your on Xeloda and even a few days after you stop- do not do anything strenuous with your feet/hands. I wouldn't jog or spend a ton of time walking around on them. The more friction to your hands and feet, the more the xeloda will leak out of those cappillaries and make the hand/foot syndrome much worse. For me, the hand and foot syndrome was torture about 3 days after I went on vacation, (zoo, museums, ballgames, walk, hot and walk some more) and similarly peaked just at the finish of my cycle of xeloda. Also you can always ice your feet/hands when it gets really bad- that does help. Hope that helps.
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[B]Kristin
Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/
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