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Old 06-14-2006, 08:52 AM   #1
R.B.
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Join Date: Mar 2006
Posts: 1,843
Strong evidence for lignans’ breast cancer protection (58% risk reduction)

There has been a lot of disucssion as to the lignans in flax seed and if they are benifical in BC and certain categories of BC (see posts on this site click on search on purple bar above and enter term flax seed flaxseed etc). There are lots of trials suggesting possible benifts from flaxseed / oil but please do look at the previous posts as the subject is not clear cut and is discussed in some detail.

This article helps clarify that you do not only find lignans in flaxseed.

One always has to be careful in assessesing data of this type as it may be there are other synegystic effects eg. those with higher lignan intake have better diets, more flavanoids folates vitamins enzymes better digestion elimination etc, less processed foods flaxseed is high in omega three etc, - but the overall direction is clear - a good diet may substantially reduce the risk of BC.

http://www.nutraingredients.com/news...-breast-cancer


ABSTRACT

Strong evidence for lignans’ breast cancer protection

By Stephen Daniells




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14/06/2006 - A high intake of plant lignans could reduce the risk of breast cancer for pre-menopausal women by 78 per cent, says new research from Germany that adds significantly to the current body of science.

Plant lignans, from sources such as flax seed, whole grain cereals, berries, vegetables and fruits, are metabolised in the colon by microflora into enterodiol and enterolactone.

Lignans are well-known phytoestrogens – active substances derived from plants that have a weak oestrogen-like action that have been linked before to breast health, as well as benefits for postmenopausal women.

The new study, published in the European Journal of Cancer Prevention (Vol. 15, pp. 225-232), reports that women with high plasma levels of enterolactone (above 12.96 nanomoles per litre), linked to high lignan intake, was associated with a 58 per cent reduction of breast cancer risk.

“To the best of our knowledge, this is the first study to investigate both calculated enterolactone on the basis of food intake and data from biomarker measurement (plasma enterolactone) in relation to breast cancer risk,” wrote lead author Regina Piller from the Technical University of Munich.

It should be stressed that this new study does not mention which source of lignans, if any in particular, the women were taking, but merely looked at total lignan intake, as well as plasma levels of the metabolite, enterolactone...............................
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