HER2 Support Group Forums - View Single Post

DianneS · 11-29-2009, 02:53 PM

I had taxotere with carboplatin and herceptin. I also had an allergic reaction to the taxotere within about 10-15 minutes of infusion - every time. They tried mixing up different pre-meds and that helped, but my infusions took 10 HOURS because they had to go so slow. They did infuse the taxotere along with saline and that seemed to help. My last infusion (#5.5) we thought we had it figured out but my bronchis went into a spasm, and that's when they infused the saline along with the taxotere. Nasty stuff.

I have heard & read that there is some synergy between carboplatin & herceptin and that TCH is a good regimen, if you can handle the taxotere. I could not do 6 sessions

Good luck,
Dianne

11-29-2009, 02:53 PM	#12
DianneS Senior Member Join Date: Aug 2008 Posts: 327	Re: Allergic reaction to taxotere I had taxotere with carboplatin and herceptin. I also had an allergic reaction to the taxotere within about 10-15 minutes of infusion - every time. They tried mixing up different pre-meds and that helped, but my infusions took 10 HOURS because they had to go so slow. They did infuse the taxotere along with saline and that seemed to help. My last infusion (#5.5) we thought we had it figured out but my bronchis went into a spasm, and that's when they infused the saline along with the taxotere. Nasty stuff. I have heard & read that there is some synergy between carboplatin & herceptin and that TCH is a good regimen, if you can handle the taxotere. I could not do 6 sessions Good luck, Dianne __________________ Three years and 5 months NED Dx: Aug 2008 right breast IDC with 50% of tumor DCIS, Stage II or IIA, tumor size: 2.1 cm Grade 3 8/9 Richardson/Bloom test ER+ weakly positive Alred Score: 4 (suggesting I would strongly benefit from hormone therapy) PR-, HER2 positive +++ No vascular invasion No lymph nodes involved Surgery: Sept. 9, 2008 -Modified radical mastectomy, right breast. I chose to have a simple mastectomy on the left. Began Taxotere/Carboplatin/Herceptin November, 2008. Finished T/C March 2009. Finished #16 Herceptin Sept. 09. AI's and Tamoxifen made me sick. Began natural Tamoxifen which is Quercetin, I3C and a combo of other supplements. I am also a DES Daughter. There is now a link between DES exposure in utero and breast cancer!