HER2 Support Group Forums - View Single Post - Tangeretin Interferes with Tamoxifen

Has any one read that Tangeretin interferes with Tamoxifen's ability to inhibit tumor growth? Tangeretin is found in the peel of citrus fruits. Does this problem also apply if you consume citrus juice such as lemon or lime juice? I always squeeze a lemon or lime in my water.

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Mammograms all along since I was 40 yrs old.
Two negative biopsies.
Mammogram in Feb 2000 at the age of 52.
Told me to return in 6 months.
BSE in Jul 2000 found lump the size of an apricot (4x2x2cm) in my left breast. Unable to be detected in mammogram.
2 encapsulated lymph nodes out of five.
ER+ Neither Her2 positive or negative.
Invasive carcinoma with small amount of duct carcinoma in situ.
Did adjuvant A/C therapy, then bi-lateral mastectomy, Taxol, radiation. DIEP reconstruction at Johns Hopkins. Tamoxifen for 3 years.
Arimidex for 5 years.

April 2009 noticed red puckering of skin site of left breast reconstruction. Oncologist thought it was benign.
Cancer returned. No metastasis.
Surgery in April 2009 of left reconstructed breast.
ER+ 90%, PR-, Her2 3+ 70%
TCH and radiation again.
One year of Herceptin (one more Herceptin and then I will be done end of April 2010).
Back on Tamoxifen.
Have not decided if I want to stay on Herceptin for another year.

04-10-2010, 10:25 AM	#1
BMW2 Member Join Date: Feb 2010 Location: Ohio Posts: 11	Tangeretin Interferes with Tamoxifen Has any one read that Tangeretin interferes with Tamoxifen's ability to inhibit tumor growth? Tangeretin is found in the peel of citrus fruits. Does this problem also apply if you consume citrus juice such as lemon or lime juice? I always squeeze a lemon or lime in my water. __________________ Mammograms all along since I was 40 yrs old. Two negative biopsies. Mammogram in Feb 2000 at the age of 52. Told me to return in 6 months. BSE in Jul 2000 found lump the size of an apricot (4x2x2cm) in my left breast. Unable to be detected in mammogram. 2 encapsulated lymph nodes out of five. ER+ Neither Her2 positive or negative. Invasive carcinoma with small amount of duct carcinoma in situ. Did adjuvant A/C therapy, then bi-lateral mastectomy, Taxol, radiation. DIEP reconstruction at Johns Hopkins. Tamoxifen for 3 years. Arimidex for 5 years. April 2009 noticed red puckering of skin site of left breast reconstruction. Oncologist thought it was benign. Cancer returned. No metastasis. Surgery in April 2009 of left reconstructed breast. ER+ 90%, PR-, Her2 3+ 70% TCH and radiation again. One year of Herceptin (one more Herceptin and then I will be done end of April 2010). Back on Tamoxifen. Have not decided if I want to stay on Herceptin for another year.