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R.B. · 09-28-2007, 02:08 PM

I wrote a considered response to this which I must have forgotten to hit the post button.

In essence it is a mix of chemistry and emotion.

One negative is bad, two is worse.

A body in balance will likely allow those inflicted with such dreadful burdens to deal with them more effectively.

Trials show norepinephrine a stress hormone is reduce by DHA

More widely omega six derived chemicals play a big part in immune response and stress response, as well as some wider emotional responses.

AA is a long chain fat which is made from omega six which is the parent of a host of inflammatory agents. As always it is a question of balance.

You don't have to understand it just get the drift as to how influential the fats are in your body.

RB

http://cat.inist.fr/?aModele=afficheN&cpsidt=15926742

ABSTRACT

Titre du document / Document title
The immunostimulating and antimicrobial properties of lithium and antidepressants
Auteur(s) / Author(s)
LIEB Julian ;
Résumé / Abstract
Eicosanoids are products of arachidonic acid (AA), an essential fatty acid. They include prostaglandins (PGs), prostacyclin (PG12), thromboxanes (TXs), leukotrienes (LTs) and hydroxy fatty acids. AA is derived enzymatically from membrane phospholipids and to a lesser extent the diet. Eicosanoids self-regulate every cell, including those synthesizing serotonin, norepinephrine and dopamine and those subserving immune function, such asT-cells, B-cells, natural killer cells, macrophages, monocytes and dendritic cells. There is objective evidence that prostaglandins regulate the physiology of the hypothalamic-pituitary-adrenal axis (HPA). Elucidation of the structure and metabolic pathways of eicosanoids galvanized researchers into illuminating their role in physiology, pathology and pharmacology. Striking contradictions arose: eicosanoids were shown to activate and suppress microorganisms, potentiate and suppress immunity and possess pro- and anticancer properties. As prostaglandins are the most heavily studied eicosanoids in the context of mood and immunity I will focus on them in this article. I will present evidence of the immunostimulating and antimicrobial properties of lithium and antidepressants and propose that these properties are linked to the antiprostaglandin actions of these compounds.

09-28-2007, 02:08 PM	#5
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	I wrote a considered response to this which I must have forgotten to hit the post button. In essence it is a mix of chemistry and emotion. One negative is bad, two is worse. A body in balance will likely allow those inflicted with such dreadful burdens to deal with them more effectively. Trials show norepinephrine a stress hormone is reduce by DHA More widely omega six derived chemicals play a big part in immune response and stress response, as well as some wider emotional responses. AA is a long chain fat which is made from omega six which is the parent of a host of inflammatory agents. As always it is a question of balance. You don't have to understand it just get the drift as to how influential the fats are in your body. RB http://cat.inist.fr/?aModele=afficheN&cpsidt=15926742 ABSTRACT Titre du document / Document title The immunostimulating and antimicrobial properties of lithium and antidepressants Auteur(s) / Author(s) LIEB Julian ; Résumé / Abstract Eicosanoids are products of arachidonic acid (AA), an essential fatty acid. They include prostaglandins (PGs), prostacyclin (PG12), thromboxanes (TXs), leukotrienes (LTs) and hydroxy fatty acids. AA is derived enzymatically from membrane phospholipids and to a lesser extent the diet. Eicosanoids self-regulate every cell, including those synthesizing serotonin, norepinephrine and dopamine and those subserving immune function, such asT-cells, B-cells, natural killer cells, macrophages, monocytes and dendritic cells. There is objective evidence that prostaglandins regulate the physiology of the hypothalamic-pituitary-adrenal axis (HPA). Elucidation of the structure and metabolic pathways of eicosanoids galvanized researchers into illuminating their role in physiology, pathology and pharmacology. Striking contradictions arose: eicosanoids were shown to activate and suppress microorganisms, potentiate and suppress immunity and possess pro- and anticancer properties. As prostaglandins are the most heavily studied eicosanoids in the context of mood and immunity I will focus on them in this article. I will present evidence of the immunostimulating and antimicrobial properties of lithium and antidepressants and propose that these properties are linked to the antiprostaglandin actions of these compounds.