[donocco]

Billie

I did some very quick research. They are starting to do the same thing with Herceptin ie giving it subcurtaneously combined with Hyaluronidase (probably to improve the relatively
poor subcutanous absorbtion). The reasoning behind these trials is that IV administration
is time consuming for the patient and health care system. As time is money as the old saying goes and health insurance companies are a major component of the health care system my cynical response might not be that far off. What they are trying to do is determine a subcutaneous dose that will give the same blood levels as the IV dose. The reasoning behind this is not to increase response but to save time and money. Im very conservative. My reasoning is "if it aint broke dont fix it. Personally Id avoid this. However talk with your Oncologist about it.

Paul