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Dear MJo,
I only have a minute but wanted to expalin something re: BRCA. IF you have a mutation in the family you have a 50% chance of inheriting it. If for some reason both parents have a BRCA mutation that increases the odds to 75% (if they are different mutations). The BRCA genetic mutations follow
"autosomal dominant" patern of inheritance which means it does not "skip" a generation. Not everyone that carries a mutation of one of the BRCA genes goes on to develope cancer. In fact studies revealed that the incidence of cancer in BRCA+ men and women showed a marked increase in occurence in those born after 1950.
. The theory
is that because we have added so many pollutants, (fertilizer,pesticides etc) to our environment a SECOND incident to the already mutated gene "triggers /
allows" the cancer to develope.
I am a little rusty on my stats, but I think you get the gist of it.
Hope this was helpful,
Marcia
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