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R.B. · 08-02-2006, 02:26 AM

It is pleasing to see trials slowly heading in this direction.

I'm afraid the more I read the more screamingly obvious it become that this is a low risk nutritional approach that may significanlty benift a very large number of peoples by potentially redcuing risk profiles of a number of diseases.

Do I not sense a degree of frustation in others too?

"and particularly beneficial to the approximately 80 million baby boomers that will begin turning 60 years of age in 2 years [2], and those who follow."

ABSTRACT

The yin and yang of 15-lipoxygenase-1 and delta-desaturases: Dietary omega-6 linoleic acid metabolic pathway in prostate
Uddhav Kelavkar, 1 Yan Lin,2 Doug Landsittel,3 Uma Chandran,4 and Rajiv Dhir4

http://www.pubmedcentral.gov/article...medid=16566819

". This study suggests that an increase in the n-6 to n-3 PUFA ratio in diet when the n-6 enzymes such as 15-LO-1 and COX-2 are aberrantly expressed can promote PCa, and the need for designing promising early dietary intervention agents such as the omega-3 fatty acids as substrate competitors of LA/AA, aimed primarily at high 15-LO-1 and COX-2 as the molecular targets (Figure 1). Early introduction of "good" metabolites by dietary n-3 PUFA thereby reducing the "bad" metabolites of dietary n-6 can slow down or even inhibit PCa development in individuals with aberrant 15-LO-1 and COX-2 expressions. Thus, by combining a reduction of dietary n-6 fat with an intake of n-3 fatty acids would be more attainable and particularly beneficial to the approximately 80 million baby boomers that will begin turning 60 years of age in 2 years [2], and those who follow."

08-02-2006, 02:26 AM	#2
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	It is pleasing to see trials slowly heading in this direction. I'm afraid the more I read the more screamingly obvious it become that this is a low risk nutritional approach that may significanlty benift a very large number of peoples by potentially redcuing risk profiles of a number of diseases. Do I not sense a degree of frustation in others too? "and particularly beneficial to the approximately 80 million baby boomers that will begin turning 60 years of age in 2 years [2], and those who follow." ABSTRACT The yin and yang of 15-lipoxygenase-1 and delta-desaturases: Dietary omega-6 linoleic acid metabolic pathway in prostate Uddhav Kelavkar, 1 Yan Lin,2 Doug Landsittel,3 Uma Chandran,4 and Rajiv Dhir4 http://www.pubmedcentral.gov/article...medid=16566819 ". This study suggests that an increase in the n-6 to n-3 PUFA ratio in diet when the n-6 enzymes such as 15-LO-1 and COX-2 are aberrantly expressed can promote PCa, and the need for designing promising early dietary intervention agents such as the omega-3 fatty acids as substrate competitors of LA/AA, aimed primarily at high 15-LO-1 and COX-2 as the molecular targets (Figure 1). Early introduction of "good" metabolites by dietary n-3 PUFA thereby reducing the "bad" metabolites of dietary n-6 can slow down or even inhibit PCa development in individuals with aberrant 15-LO-1 and COX-2 expressions. Thus, by combining a reduction of dietary n-6 fat with an intake of n-3 fatty acids would be more attainable and particularly beneficial to the approximately 80 million baby boomers that will begin turning 60 years of age in 2 years [2], and those who follow."