HER2 Support Group Forums - View Single Post - for those with micromets or individual cytokeratin+ cells in their sentinel nodes...

RobinP · 06-13-2006, 07:08 AM

Research is continuing via the Z0010 for less than .02mm. Dr. Borgen, from MSK, has done a lot of research, indicating that isolated tumor cells and clusters are real cancer cells and not just reactive epithelial cells so this is why the ZOO10 may be so important. The ZOO10 continues to see if these are prognostically significant and may define if they are true metastases or mechanically displaced cells orginating from the orginal tumor biopsy(s). When it comes to ITC or clusters, I think that the addition of positive LVI- lymphatic invasion may only heighten the concern of their orgin.

06-13-2006, 07:08 AM	#5
RobinP Senior Member Join Date: Nov 2005 Posts: 943	Research is continuing via the Z0010 for less than .02mm. Dr. Borgen, from MSK, has done a lot of research, indicating that isolated tumor cells and clusters are real cancer cells and not just reactive epithelial cells so this is why the ZOO10 may be so important. The ZOO10 continues to see if these are prognostically significant and may define if they are true metastases or mechanically displaced cells orginating from the orginal tumor biopsy(s). When it comes to ITC or clusters, I think that the addition of positive LVI- lymphatic invasion may only heighten the concern of their orgin. __________________ Robin 2002- dx her2 positive DCIS/bc TX Mast, herceptin chemo Last edited by RobinP; 06-13-2006 at 07:11 AM..