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Many Questions for EARLY STAGERS!
dx. with microinvasion of in situ duct carcinoma (DCIS)
Bloom Richardson grade 1
3MM microsopic
No angiolymphatic invasion is identified
DCIS is predominantly cribriform type with intermediate grade nuclei
The resection margins are free of invasive and in situ carcinoma
Microcalcification are associated with DCIS
FISH test - Her2 +++ positive
Estrogen Recetpor: 90% positive
Progesterone Receptor 1% negative
Proliferation Index: 40%
Sentinal Node biopsey - Negative
Onctoype DX test - recurrance score high range 31%
Was advised to treat with lumpectomy - had 25MM clean margins
Radiation 32 treatments
Arimidex
After Oncotype test score came back in the high range saw Dr. Slamon
who advised chemo/taxol/herceptin. I am now one yr. out!
Will begin treatments in the next two weeks.
Dr. Slamon ordered TOPO 11 test (will get results this week)
and also having PTEN test done which is a predictor of who will respond to
herceptin.
Have also contacted Dr. Greene in Penn U - for information on trial for blood test to test for her2 neu proteins. (will know more this week)
I have decided that the dr. are treating the early stagers not as serious
as they should and WE MUST be diligent in our medical needs. I am just sorry I lost the time - but hopefully I will catch up now. I had PET scans and CT scans plus bone scans done, all came back NED (thank God). I am approaching this now as if I found my cancer 6 months ago and going after it with a strong approach. Even though small tumors and node negative are favorable factors I no longer believe that is enough to base treatment decisions on. The make up of the tumor like your own personal fingerprint is the key.
I think all early stagers need to be very careful and ask what your Ki-67 level is - since that is a strong indicator.
Thank you Lani for Posting, I hope that some solid research will come form this.
Regards,
Jean
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