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Lani · 04-24-2006, 02:47 PM

WERE you ER or PR positive and are you also on an antihormonal? Were you made postmenopausal by your chemo? Just not having estrogen around seems to be enough to cause it hard to find words, have trouble with short term memory and lots more. Estrogen seems to be necessary for optimal brain functioning(think of those poor men!) especially communication between nerve cells. Obviously many women have been treated with aromatase inhibitors, which inhibits one of three enzymes making estrogen in postmenopausal women, and they "seem OK" but I wonder if a careful questioning of those breast cancer patients in Europe who got aatihormonals but not chemo for early breast cancer, would lead to identification of an "estrogen-starved brain" syndrome. Just food for thought!

04-24-2006, 02:47 PM	#2
Lani Senior Member Join Date: Mar 2006 Posts: 4,778	questions WERE you ER or PR positive and are you also on an antihormonal? Were you made postmenopausal by your chemo? Just not having estrogen around seems to be enough to cause it hard to find words, have trouble with short term memory and lots more. Estrogen seems to be necessary for optimal brain functioning(think of those poor men!) especially communication between nerve cells. Obviously many women have been treated with aromatase inhibitors, which inhibits one of three enzymes making estrogen in postmenopausal women, and they "seem OK" but I wonder if a careful questioning of those breast cancer patients in Europe who got aatihormonals but not chemo for early breast cancer, would lead to identification of an "estrogen-starved brain" syndrome. Just food for thought!