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03-10-2006, 05:00 AM

Heart health and omega three derivatives DHA and EPA found in fish oil.

The body can make EPA and DHA but it is dependent on the efficient functioning of the body which can be upset in lots of ways.

It is equally important to balance the threes and sixes.

RB

http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

1: Curr Atheroscler Rep. 2004 Nov;6(6):447-52. Related Articles, Links
Click here to read
Are omega-3 fatty acids the most important nutritional modulators of coronary heart disease risk?

Harris WS.

St. Luke's Mid America Heart Institute and Department of Medicine, University of Missouri-Kansas City School of Medicine, 4320 Wornall Road, Suite 128, Kansas City, MO 64111, USA. wharris@saint-lukes.org

With each passing year, the evidence linking an increased risk for coronary heart disease (CHD) death with a chronic dietary deficiency in long-chain omega-3 (n-3) fatty acids (FAs) grows stronger. Recently, a federally mandated evidence-based review in the United States concluded that n-3 FAs, especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have clear cardioprotective effects, and national and international expert panels and health organizations have begun to call for increased EPA and DHA intakes. Consumption of between 450 and 1000 mg/d is recommended for those without and with known CHD, respectively. Based on animal and isolated cell studies, these FAs were presumed to have antiarrhythmic effects. The first direct evidence for this in humans was recently published, as were new data linking low n-3 FA intakes with risk for developing atrial fibrillation. The strength of the n-3 story has now led to a proposal that blood levels of EPA plus DHA be considered a new, modifiable, and clinically relevant risk factor for death from CHD.

Publication Types:

* Review

PMID: 15485590 [PubMed - indexed for MEDLINE]

03-10-2006, 05:00 AM	#7
Unregistered Guest Posts: n/a	Heart health and omega three derivatives DHA and EPA found in fish oil. The body can make EPA and DHA but it is dependent on the efficient functioning of the body which can be upset in lots of ways. It is equally important to balance the threes and sixes. RB http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum 1: Curr Atheroscler Rep. 2004 Nov;6(6):447-52. Related Articles, Links Click here to read Are omega-3 fatty acids the most important nutritional modulators of coronary heart disease risk? Harris WS. St. Luke's Mid America Heart Institute and Department of Medicine, University of Missouri-Kansas City School of Medicine, 4320 Wornall Road, Suite 128, Kansas City, MO 64111, USA. wharris@saint-lukes.org With each passing year, the evidence linking an increased risk for coronary heart disease (CHD) death with a chronic dietary deficiency in long-chain omega-3 (n-3) fatty acids (FAs) grows stronger. Recently, a federally mandated evidence-based review in the United States concluded that n-3 FAs, especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have clear cardioprotective effects, and national and international expert panels and health organizations have begun to call for increased EPA and DHA intakes. Consumption of between 450 and 1000 mg/d is recommended for those without and with known CHD, respectively. Based on animal and isolated cell studies, these FAs were presumed to have antiarrhythmic effects. The first direct evidence for this in humans was recently published, as were new data linking low n-3 FA intakes with risk for developing atrial fibrillation. The strength of the n-3 story has now led to a proposal that blood levels of EPA plus DHA be considered a new, modifiable, and clinically relevant risk factor for death from CHD. Publication Types: * Review PMID: 15485590 [PubMed - indexed for MEDLINE]