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Old 12-22-2005, 04:37 PM   #11
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Younger women - fertility - sexuality - early menopause

Rupali

I am man and not a sufferer so I can only begin to imagine the impact of the questions you are facing.

From what I have read some things are clear;
1. The group with highest treatment dissatisfaction is young women.
2. It is recogised that in many instances young women are not sufficiently informed from within the "system". The emphasis is often on any level of potential survival gain, no matter what the outcome in terms of fertility / sexuality. It appears from literature that treatment issues are often not weighed against fertility, energy, general well being, sexuality etc.
3. There are limited statistics for the fertile sufferers group.
4. There is conflict as to the impact of retained fertility (oestrogen etc) on re occurence / survival and hence some people who retain fertility are ablated surgically or chemically. There are a lot of trials looking at the outcome statistics which might be of interest to you.
5. I have seen some suggestion that some chemical ablation is reversible in terms of fertility sexuality.
6. I will post a very powerful poem from a sufferer that gives a pesonal perspective from one set of circumstances on a separate post.
7. Subsequent fertility / impact of pregnancy is an issue on its own. Statistics are again limited, but look grimer than often portrayed.
8 HRT use is reported as carrying a high risk. Natural hormone replacement is discouraged.

I have included a rather lengthy list of links I have saved at one point or another that deal with aspects of the subject. I suggest you skim through them as a minimum, and I suspect it will become evident to you that you are potentially faced with huge life decisions, which justify as much research as you have time for. You with your advisors will have to weigh the different risk profiles, monitoring options, treatment side effects etc. There are real choices. My instinct is that as a minimum being as informed as possible outcomes and options will reduce the potential for what if's at a future date.

I hope you find the links useful. You are your own best advocate, and I have no words to begin to understand the decisions you face.

RB



Information

http://store.yahoo.com/annieapplesee...nwomproba.html

http://www.cancerline.com/cancerline...261_2_0_0.aspx

http://www.jco.org/cgi/content/full/23/19/4259

http://www.abreastinthewest.ca/news2.cfm?Num=52

http://jncicancerspectrum.oxfordjour...ono;2005/34/40

http://www.allheadlinenews.com/articles/2236462302

http://www.cancer.org/docroot/MED/co...p?sitearea=MED

http://caonline.amcancersoc.org/cgi/.../full/55/4/211

http://medicineworld.org/cancer/lead...fertility.html

http://www.komen.org/stellent/groups.../spbcyoung.pdf

http://www.asco.org/ac/1,1003,_12-00...-004265,00.asp

http://my.webmd.com/content/article/95/103281.htm

http://store.yahoo.com/annieapplesee...ct/chemam.html

http://www.emaxhealth.com/98/2223.html

http://www.bcaction.org/Pages/Search...etter049C.html

http://www.sciencedaily.com/releases...0203234441.htm

http://www.nci.nih.gov/cancertopics/...e7#Section_261

http://www.nci.nih.gov/cancertopics/...e7#Section_261

http://www.thelocal.se/article.php?I...&date=20050901

http://www.sciencedaily.com/releases...0413064628.htm

http://www.nci.nih.gov/cancertopics/.../Patient/page6

http://store.yahoo.com/annieapplesee...ct/chemam.html

http://professional.cancerconsultant....aspx?id=29053

http://professional.cancerconsultant....aspx?id=29165

http://professional.cancerconsultant....aspx?id=29170





STATISTICS

http://www.cancernews.com/articles/cancer&fertility.htm

http://professional.cancerconsultant....aspx?id=31354


ARTICLES

Avis NE et al. Psychosocial problems among younger women with breast cancer. Psychooncology 2004;13(5):295-308. Abstract

Brenner H, Hakulinen T. Are patients diagnosed with breast cancer before age 50 years ever cured? J Clin Oncol 2004;22(3):432-8. Abstract

Casso D et al. Quality of life of 5-10 year breast cancer survivors diagnosed between age 40 and 49. Health Qual Life Outcomes 2004;2(1):25. Abstract
Chia KS et al. Do younger female breast cancer patients have a poorer prognosis? Results from a population-based survival analysis. Int J Cancer 2004;108(5):761-5. Abstract

Curigliano G et al. Adjuvant therapy for very young women with breast cancer: Response according to biologic and endocrine features. Clin Breast Cancer 2004;5(2):125-30. Abstract

Foxcroft LM et al. The diagnosis of breast cancer in women younger than 40. Breast 2004;13(4):297- 306. Abstract

Friedlander M, Thewes B. Counting the costs of treatment: The reproductive and gynaecological consequences of adjuvant therapy in young women with breast cancer. Intern Med J 2003;33(8):372-9. Abstract

Ganz PA et al. Breast cancer in younger women: Reproductive and late health effects of treatment. J Clin Oncol 2003;21(22):4184-93. Abstract
Grosser L. Meeting the needs of younger women with breast cancer. Nurs Times 2003;99(42):20-2. Abstract

Phillips KA et al. Prognosis of premenopausal breast cancer and childbirth prior to diagnosis. J Clin Oncol 2004;22(4):699-705. Abstract

Thewes B et al. The psychosocial needs of breast cancer survivors; a qualitative study of the shared and unique needs of younger versus older survivors. Psychooncology 2004;13(3):177-89. Abstract






Fertility Links

http://www.ons.org/publications/jour...e3/3103515.asp

http://www.fertilehope.org/
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