HER2 Support Group Forums - View Single Post - A Little Light? Flax Seed And Phytoestrogens

12-12-2005, 03:11 PM

A very kind commentator in response to an enquiring email from me on flax oil, flax seed, phytoestrogens to whom I gave the link to our posts below. It might be of interest to your oncologist.

RB

ABSTRACT

"There seems to be a lot of confusion on the website below. I will
attempt to answer some of the questions posted on this site: firstly,
flax oil does not contain any lignans as they do not dissolve in oil.
Lignans are present in every plant food that we eat only more
concentrated in flax and therefore commercially more viable to extract.
There is products available on the market that do deliver specific
quantities of flax lignans.

Lignans are phytoestrogens but they are very weak and only elicit a
very weak estrogenic response. The current research suggests that the
advantage of this is the body detects them as estrogens (which produce a
strong estrogenic response) and therefore produces less harmful
estrogens (homoeostatic process) though inhibition of the aromatase
enzymes, more SHBG to bind estrogens (for elimination from the body) and
increases the conversion of estrogens to the 2OHE metabolism pathway
over the 16OHE (by increasing CYP1A1 enzymes). This whole process has a
cyclic effect with the end result being less bioavailable estrogen
(harmful), increased 2OHE (protective), and decreased 16OHE (harmful)."

12-12-2005, 03:11 PM	#1
Unregistered Guest Posts: n/a	A Little Light? Flax Seed And Phytoestrogens A very kind commentator in response to an enquiring email from me on flax oil, flax seed, phytoestrogens to whom I gave the link to our posts below. It might be of interest to your oncologist. RB ABSTRACT "There seems to be a lot of confusion on the website below. I will attempt to answer some of the questions posted on this site: firstly, flax oil does not contain any lignans as they do not dissolve in oil. Lignans are present in every plant food that we eat only more concentrated in flax and therefore commercially more viable to extract. There is products available on the market that do deliver specific quantities of flax lignans. Lignans are phytoestrogens but they are very weak and only elicit a very weak estrogenic response. The current research suggests that the advantage of this is the body detects them as estrogens (which produce a strong estrogenic response) and therefore produces less harmful estrogens (homoeostatic process) though inhibition of the aromatase enzymes, more SHBG to bind estrogens (for elimination from the body) and increases the conversion of estrogens to the 2OHE metabolism pathway over the 16OHE (by increasing CYP1A1 enzymes). This whole process has a cyclic effect with the end result being less bioavailable estrogen (harmful), increased 2OHE (protective), and decreased 16OHE (harmful)."