Yes, in both her-2 women with metastatic breast cancer
(source:
http://www.ncbi.nlm.nih.gov/entrez/q...83&query_hl=14)
and in er- women in general: (sources, among others
http://www.ncbi.nlm.nih.gov/entrez/q...65&query_hl=14
http://www.ncbi.nlm.nih.gov/entrez/q...05&query_hl=14)
Apparently this was first recognized way back in 1981!