Port + neo-adjuvant chemo is the way to go on large tumors. The tumor down-sizing will most likely put your wife in the position of opting for a lumpectomy, which has the same survival rate in this case as a mastecomy. The port will give her added convenience for infusions. My wife puts a lidocaine gel on the port 1 hour before infusion; this makes the process painless.
Good luck,
Al
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Primary care-giver to and advocate for Linda, who passed away April 27, 2006.
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