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I have been fighting this battle with my onc. for 6 months. I am on zoladex shots and tamoxifen. I want to switch but she's making me wait until I hit the 2 year mark. There is some antedotal evidence that tamoxifen counteracts herceptin. Al from Canada has some good links on it. I hope that both add incremental benefit, it's just a matter of which adds more.
The bottom line is that there's not a lot of studies on women who are premenopausal and put into chemical menopause comparing the two. I believe eventually it will show AIs are superior for people like us, but there have not been any large studies that have determined that yet. The most important thing is that if you want to do and AI make SURE you are menopausal for several months first. Taking an AI if you are still ovulating is bad news.
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