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Hi Claudia,
Yes, of course. There have been many and many are going on as well. The reason why this is big news is that this is the first evidence that herceptin by itself after chemo makes a big difference in preventing BC recurrence. Up to now in many countries it has been nearly impossible to get herceptin until the BC came back. This trial results indicates that herceptin is much more effective when used early.
The participants in the trial needed to be diagnosed with primary breast cancer, been diagnosed as strongly HER2-positive (e.g. IHC3+ and/or FISH+), and have completed a course of standard systemic chemotherapy (standard chemotherapy administered before or after surgery) prior to enrolment.
The full details of the HERA results are not out yet, but probably will be later today.
Best wishes,
Christine
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