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Was this your first dose of herceptin? IF so as I said to Colleen in regards to her mom, it is very rare to react a second time. I reacted with severe shakes (rigors) and a fever. They immediately gave me benadryl and then resumed the drip an hour later very slowly. The next treatment, I received benadryl IV prior to my herceptin, a slower infusion and all has been well since. I still get benadryl and my infusion rate is normal. I hope that is helpful.
Elisabeth
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