Re: SABCS: Tucatinib 'game changing' vs HER2+ MBC, especially w brain mets
Lani
This is good news. Tucatinib is the drug that went by the experimental name of ONT-380 or something like that, correct. If it is it has good central nervous system penetration and the diarrhea is less than Tykerb because Tucatinib only acts on Her-2 not on Her-1. It seems to be a definite advance.
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