HER2 Support Group Forums - View Single Post - Resveratrol--interpret this article?

VDC · 05-31-2016, 11:37 PM

I'll see if I can find the osteoarthritis study. I look to these studies to determine what dosage might be appropriate. The in vitro studies are interesting and may or may not hold true in vivo, but regardless, in vitro studies give no indication what dosage might be effective in vivo. Even if applied to osteoarthritis, it still gives some indication what dosage has been used safely in human subjects.

edit: Found 'em!

http://www.news-medical.net/news/2008/12/10/44001.aspx

The article above is for the lay person while the article below is the original article

http://www.ncbi.nlm.nih.gov/pubmed/19017467

This study suggests 100 mg daily for osteoarthritis. When I looked at Pycnogenol to purchase, it wasn't quite as clear. Most Pycnogenol is labeled as such, BUT when you look at the labels they are labeled as "Pine Bark Extract" standardized to 70% procyanidins. Makes me wonder how much of those procyanidins are actually pycnogenol! There doesn't appear to be a way to determine the exact amount of pycnogenol in each supplement. I went with a supplement called "Pine Bark Extract" rather than one labeled "Pycnogenol" because it actually had a GREATER percentage of procyanidins! Go figure!

05-31-2016, 11:37 PM	#31
VDC Senior Member Join Date: Jan 2016 Posts: 122	Re: Resveratrol--interpret this article? I'll see if I can find the osteoarthritis study. I look to these studies to determine what dosage might be appropriate. The in vitro studies are interesting and may or may not hold true in vivo, but regardless, in vitro studies give no indication what dosage might be effective in vivo. Even if applied to osteoarthritis, it still gives some indication what dosage has been used safely in human subjects. edit: Found 'em! http://www.news-medical.net/news/2008/12/10/44001.aspx The article above is for the lay person while the article below is the original article http://www.ncbi.nlm.nih.gov/pubmed/19017467 This study suggests 100 mg daily for osteoarthritis. When I looked at Pycnogenol to purchase, it wasn't quite as clear. Most Pycnogenol is labeled as such, BUT when you look at the labels they are labeled as "Pine Bark Extract" standardized to 70% procyanidins. Makes me wonder how much of those procyanidins are actually pycnogenol! There doesn't appear to be a way to determine the exact amount of pycnogenol in each supplement. I went with a supplement called "Pine Bark Extract" rather than one labeled "Pycnogenol" because it actually had a GREATER percentage of procyanidins! Go figure!