[phil]

That FDA official, richard klein , mentioned in the CNN story is way out of touch with reality . It's true, his agency granted 900 out of 904 comp use requests in 2012 , but that is a patheticaly low no. in a country of 360 million. and it sounds like the rubber stamp, redtape delays that we talk about eliminating with right to try. and his un-predictable, punitive fda since 2009 only makes co.'s more paranoid. and we stage iv pay the price with our lives. not that co's are blameless- $ is always a factor in their decisioon making. $ means co.'s will only make so much of a drug , even as phase I and often phase II data suggest efficacy - 38 % of pts in phase II trials of t dm-1 in early 2010 showed a" complete or significant " clinical response. yet fda rejected early appr. now comes palbociclib , with even better stats - still taking yrs to appr., still not appr. , its coming soon - but is Pfizer making enough ?