[CarolineC]

Thank you all for your responses! Karina14 hopefully your current treatment will be effective. How are you handling it? What are you taking as a bone remodeller? Maybe if your mets get stable they should keep you at weekly.

StephN thank you for responding. I have noticed before in your signature line of your weekly treatment. Andi also had it for a number of years. Karen was having weekly treatments before they moved her to every 3 weeks and she recurred. I was just thinking that maybe some of us need to have Herceptin in our system more often because we're possibly clearing it too fast, or possibly a dual blockade with Perjeta or chemo or all three like Rachael and Flori.

Rachael, thank you for the link! I haven't contacted Genentech yet, but I will. I also remembered I met with a doctor over two years ago who was the head of the Neratinib clinical trial in Vancouver. He is the head of the tumour board, I was told by a BC Cancer Agency pharmacist, and maybe he'll have answers to my questions.

I've decided I am going to take a break for a while and just enjoy the upcoming month before I have to deal with scans and the roller coaster. The last few months have been so busy with appointments and scans and reactions to scan solution and Pamidronate. I had a Herceptin treatment last Thursday, we went to Spokane, WA on Friday for my birthday and I was pretty tired on the weekend-we didn't return until Sunday. It was so nice to get away and rejuvenate and today I felt pretty good.

Love to all of you,

Caroline