['lizbeth]

The higher amount of Taxotere in the TH was too much for me. My nurse took pity and did a dose reduction to the TCH level for me, and it still didnt feel like this "doable" that everyone says. I'm starting to think everyone has a much more efficient liver than I.

KDR, I'm sorry but you won't be allowed to exit stage left in 10-11 months, we very much like having you as a fellow poster on the board. Remember Christine survived 20 years after having brain mets, and that was before all the additional treatments that are now available. So plan for the best as well as the worst!

Benjamin, honestly if I had to pick a treatment these days I'd enroll the ATEMPT trial and be randomized to TH or TDM1. You can also check out the I-Spy trial. This is, if your wife's BRCA test came back negative.

http://www.clinicaltrials.gov/ct2/show/NCT01853748

I had Taxotere, this study uses the other taxane Paclitaxel, which is similar.

I-SPY link:
http://www.clinicaltrials.gov/ct2/sh...y+stage&rank=8

With as concerned as you are, a clinical trial, which is expected to have effectiveness better than standard of care (TCH) might be a better decision. Keep in mind currently your wife is NED, no evidence of disease which means cancer free. So you can relax a little about making a choice. If you go with the most popular choice TCH - it still is a good decision. But she won't be doing anything to improve standard of care for others, nor will she receive the benefit of cutting edge research. And if the BRCA testing is positive, you must consider TCH and research platinum salts. Just my humble opinion.

Jackie, did you copy the wrong post? That compares ACTH to TCH, not TH to TCH.