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Old 03-30-2013, 07:36 PM   #9
Debbie L.
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Join Date: Jul 2006
Posts: 463
Re: Friend newly DX Er/pr+,Her2+ less than 1 cm.

Marcia, I think it's probably the same treatment choices regardless (of stage) for most HER2+ cancer, unless she would like to explore clinical trials.

But . . . if she doesn't know nodal status, she doesn't (yet) know what stage the cancer is.

The NCCN guidelines aren't a bad place to begin looking at standard-of-care choices:

http://www.nccn.org/professionals/ph...lines.asp#site

(to go farther than the link above, choosing "breast cancer", requires me to log in, so I stopped at that link. I don't think the internet police will come after you if you say you're a medical professional to get in -- or you could choose "patient guidelines" and see if that's enough information)

Debbie Laxague
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3/01 ~ Age 49. Occult primary announced by large (6cm) axillary node, found by my husband.
4/01 ~ Bilateral mastectomies (LMRM, R elective simple) - 1.2cm IDC was found at pathology. 5 of 11 axillary nodes positive, largest = 6cm. Stage IIIA
ERPR 5%/1% (re-done later at Baylor, both negative at zero).
HER2neu positive by IHC and FISH (8.89).
Lymphovascular invasion, grade 3, 8/9 modified SBR.
TX: Control of arm of NSABP's B-31 adjuvant Herceptin trial (no Herceptin, inducing a severe case of Herceptin-envy): A/C x 4 and Taxol x 4 q3weeks, then rads. Raging infection of entire chest after small revision of mastectomy scar after completing tx (significance unknown). Arimidex for two years, stopped after second pathology opinion.
2017: Mild and manageable lymphedema and some cognitive issues.
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