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Old 02-27-2013, 07:10 AM   #8
KristinSchwick
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Join Date: Jun 2011
Location: Iowa
Posts: 231
Re: To Anne, our dentist: Biosulphonates and osteonecrosis

So I have not had any problems with my teeth during my treatments (Xgeva/denosumab) for almost 2 years. No cavities, no extractions. But for the past 3 days, I've had some tooth pain- and I'm worried that it could be ONJ.

I just had a brain MRI, that showed a perfectly healthy brain- but I'm wondering if they looked carefully at my jaw too. I know if it was super obvious they'd probably see ONJ, but would they see a really small area of ONJ? Also do the routine X-Rays done during dental exams pick up ONJ? Thanks,
Kristin
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[B]Kristin
Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/
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