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Old 02-18-2013, 11:14 PM   #7
Pamelamary
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Join Date: Apr 2012
Location: Melbourne, Australia
Posts: 494
Re: Plans have changed

Hi Penny,
After 6 treatments, i felt I had had enough - the mets had shrunk to almost nothing and I was feeling lousy. So it was always planned to have as much as I could take, then see how the Herceptin held.
It was very much cumulative with me; at first I was going fine, but by the end I was extremely tired and getting all sorts of minor infections, as well as neuropathy. You can't predict how it will affect you. I know others have had many more doses - and if it works!!?!?
I hope it does the trick for you.
Beat wishes..... Pam
__________________
Diagnosed 2004: Lumpectomy - 2 tumours, both grade 1 infiltrating duct carcinoma, about 12mm. ER+,
C-erbB-2 status 3+.
Clear margins, no nodal involvement.
Radiotherapy, i year Tamoxifen, 4 years Arimidex.
Rediagnosed 2012: Multiple bone metastases.
3/12: began on Marianne trial - T-DM1 + Pertuzamab/Placebo.
5/12:Unexpected development of numerous bilateral liver mets. Came off trial.
Started Docetaxol/ Herceptin + Zometa.
8/12:Bones stable +major regression in liver (!)
9/12:Can't take any more Docetaxol! Start on Herceptin and Tamoxifen. Cross fingers!
Changed to Denosumab.
11/12: Scan shows stable - yay!
11/13: Still stable :-) !!!
1/16: All stable, but lowered calcium, so switched to Zometa 3 monthly.
2/19: Happily still stable on Herceptin, Letrozole and 3 monthly Zometa.
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