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Old 02-12-2013, 06:52 AM   #4
rhondalea
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Join Date: Jun 2011
Location: Somerset, NJ
Posts: 487
Re: Work stress and risk of cancer

IMO, this week's study is next week's debunked theory. I know that isn't always true, but it happens often enough that I want to beat my head against the wall. (Just look at the CYPD26 study for tamoxifen patients as an example. My onc tried to pacify me with one out of about 16--the one that "proved" her point that I shouldn't worry about my intermediate metabolizer status--but very recently, she has been debunked. Thoroughly. At least until the next study.)

I think stress hormones have the ability to do the same bad things that external toxins do. So it's probably not stress so much as how an individual responds to stress. But what's nice about studies like this is that they can help put an end to idiotic suggestions--you know, the ones that blame the victim.

To me, cancer is a genetic issue, so what starts it for one of us will not start it for the rest of us. I've been pretty sure all along that mine was triggered by my thyroid, and recently, I've needed far less thyroid replacement hormone than I did when my cancer was growing. But that's probably just one piece of it, even if it's where I put the blame.

I keep hoping for faster advances in genetic and epigentic medicine, and it seems as if the scientific community is trying to oblige, but there's just so much data to sift through--there are millions of snps on our genes, and figuring out which ones do what is a tedious process.

But for anyone who has an irritating onc (or friend) who suggests "reducing stress," this makes a nice study to shut him/her/it up with.
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2/6/09 Core needle biopsy: negative; Mammos through 2010: no change
3/30/11 Pea-sized lump in left breast at site of prior biopsy; mammo negative, sonogram not so much
4/14/11 Core needle biopsy: negative for cancer
5/18/11 Excisional biopsy 1.2 cm tumor, LVI, positive margin; ER+60%,PR+20%,HER2/CEP17 5
6/15/11 BMX: Left DCIS & LH; Right ADH; SNB: 2/3 nodes: 1.4 cm and 1 mm; ALND L1&2: 0/10; Stage IIa, Grade 3
7/14/11 CT/Bone scans NED; MUGA 66%
7/19/11 Biweekly dd AC w/Neulasta; done 8/30/11
9/13/11 Transfusion (Hemoglobin 8.6); MUGA 64%
9/20/11 Start Taxol + Herceptin; Taxol done 12/6/2011; continue Herceptin until 9/4/2012
12/27/11 Radiation - 6 weeks; 2/27/2012 - DONE! Yayyyy!
2/29/12 Start Tamoxifen 20 mg/day; continue until 2/28/17
5/16/12 Start five-years Metformin trial
6/19/12 MUGA 61%
8/21/12 Brain MRI NED (head still hurts, brain still fogged)
9/4/12 Herceptin done!
9/6/12 Port out!
7/11/13 Aricept 5mg for cognitive impairment; increased to 10mg as of 8/23/13; back to 5mg 12/2013
5/2014 Add Namenda 7mg
9/2014 Stop Aricept and Namenda; Neuropsychological evaluation
10/24/14 Start cognitive rehabilitation therapy
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