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Old 01-04-2013, 06:26 PM   #2
chrisy
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Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
Re: Dad will start Gemzar and Carboplatin next week

Marcia,
Sorry you are having to deal with this, and from a distance as well. I haven't had that combo (although I think it will be "next" on the list) so I can't comment directly.

I did have Carbo/Taxol/Herceptin as my first chemo and found that combination very tolerable, but then so much depends on your overall health and when I had taxol then taxotere this year I was miserable. So you just don't know.

Gemzar does not challenge hair, but can hit blood counts pretty hard. But it is generally thought to be an "easier" chemo. Carboplatin is supposed to be rougher, and neuropathy can be an issue.

Best bet is to google these for side effects, but keep in mind the list is always longer than seems necessary because it includes EVERYTHING ever reported. And most importantly, everyone does respond differently, so you don't know how your Dad will react. You can be prepared to recognize the S/E IF he experiences them, but don't claim them ahead of time,

Blessings to you and your dad.
Chris
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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