HER2 Support Group Forums - View Single Post - Need opinions/advice/prayers on liver options

Joan M · 11-21-2012, 06:18 PM

Penny,

As many on this site know, I'm very much for local procedures to target limited disease. I did this and have been NED since October 2008.

Patients have mixed results from local procedures. At the time I wanted to try it. First a lung wedge resection, and then when the cancer recurred a year later in 2008 in the same area (even though I had clean margins), I had an RFA.

I've been on only Herceptin since my disease advanced in January 2007, and I took the drug off label for 52 weeks when I was diagnosed in 2003 with stage 2B. It's like, Go figure. (I had 7 positive lymph nodes and didn't want to risk drawing the arm without Herceptin in the adjuvant trial).

I just take a wait and see approach, and hope my LVEF holds out and I'll continue to be NED.

Good luck with whichever decision you make.

Joan

11-21-2012, 06:18 PM	#18
Joan M Senior Member Join Date: Oct 2007 Posts: 1,851	Re: Need opinions/advice/prayers on liver options Penny, As many on this site know, I'm very much for local procedures to target limited disease. I did this and have been NED since October 2008. Patients have mixed results from local procedures. At the time I wanted to try it. First a lung wedge resection, and then when the cancer recurred a year later in 2008 in the same area (even though I had clean margins), I had an RFA. I've been on only Herceptin since my disease advanced in January 2007, and I took the drug off label for 52 weeks when I was diagnosed in 2003 with stage 2B. It's like, Go figure. (I had 7 positive lymph nodes and didn't want to risk drawing the arm without Herceptin in the adjuvant trial). I just take a wait and see approach, and hope my LVEF holds out and I'll continue to be NED. Good luck with whichever decision you make. Joan __________________ Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2023 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!! Last edited by Joan M; 11-21-2012 at 06:22 PM..