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Re: Waiting, waiting...
Thank you - I am all set to start tomorrow. Pity I have a cold but no reason to stop treatment.
They told me today that the trial protocol has just changed to allow all in the control arm to crossover to TDM1 upon progression - great news!
Sooo happy to be starting - I know it may not work but I feel it may just be the right thing for me. The onc said many on the drug take a while to respond and then continue to respond slowly. His best responder so far is still having reduction 12 months on.
My scans were not great although onc didn't seem concerned the report read yucky - what is it with the language. onc felt there was nothing new (feels it was all there befo just small) report said significant number of new lesions in lungs. Target lesions have grown significantly in 8 weeks and I have mediastinal and hilar lymphadenopathy not seen in previous scan (although my pet showed activity here) and a possible early node in my abdomen. Good news is my bones, live and brain and showing clear! Even better I am still asymptomatic (I have a cough currently but I have had a cold and bad hay fever - I don't feel my breathing is otherwise impaired even going for a run the other day and cycling with the kids every day this week).
So, on we go!
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Amanda xx
40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11
Wife to my wonderfully supportive husband of 17 years!
22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old
(L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins.
Fec*3, Taxotere and herceptin*2 - stopped due to secondary diagnosis
June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions
Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo
February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again
August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy!
September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing.
January 2013 - herceptin, carboplatin and Perjeta (compassionate access)
April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta
July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.
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