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Green Tea
Reported in an issue of Nutrition and Cancer, investigators had shown that in green tea, the main active component is epigallocatechin-3-gallate (EGCG). In this study, they examined the effect of green tea on breast cancer growth and endothelial cells in in vitro assays and in animal models. They compared the potency of the different catechin components of green tea extract (GTE), including EGCG. Their data showed that mixed GTE and its individual catechin components were effective in inhibiting breast cancer and endothelial cell proliferation. In mouse experiments, GTE suppressed xenograft size and decreased the tumor vessel density. Their results demonstrated the value of all catechins and argued for the use of a mixed GTE as a botanical dietary supplement, rather than purified EGCG, in future clinical trials.
Greg
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