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Old 02-12-2012, 07:04 PM   #369
Mtngrl
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Join Date: May 2011
Location: Denver, CO
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Re: The traditional diet of Greece and cancer.

Karen--

I'll take a stab at it, though R.B. is the expert. He even wrote a book on it.

In an early post it says: "The diet of our ancestors was less dense in calories, being higher in fiber, rich in fruits, vegetables, lean meat, and fish. As a result, the diet was lower in total fat and saturated fat, but contained equal amounts of n-6 and n-3 essential fatty acids. Linoleic acid (LA) is the major n-6 fatty acid, and alpha-linolenic acid (ALA) is the major n-3 fatty acid. In the body, LA is metabolized to arachidonic acid (AA), and ALA is metabolized to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)."

Translation: Nowadays, our diet has a much higher ratio of Omega 6 to Omega 3 than the diet we evolved on, both because we directly eat a lot of vegetable oils that are high in Omega 6 and because the animal foods that we consume (meat, eggs, milk, butter) have the same imbalance, because the animals were fed a high Omega 6 diet (i.e. grains and soy.)

The practical application is this: Eat a predominately plant-based diet of whole, unprocessed foods: whole grains, lots and lots of vegetables, and fruit. Eat wild, cold-water fish a few times a week. If you can get it, eat "pastured" (grass fed) meat, eggs, butter and milk. Milk from grass fed cows is higher in Omega 3 fatty acids than conventional milk, and it has conjugated linoleic acid, which is good for you, and which conventional milk does not have. If you can't get red meat, chicken, eggs and dairy foods from grass fed animals, consider skipping them or severely limiting them. (Nonfat dairy foods should be alright--no fat means no imbalance of fats, I should think.) Don't eat anything fried. Use just a little olive oil on your salads. Avoid all trans fats (hydrogenated fats). Avoid or limit added sugar. Don't use artificial sweeteners.

You might want to take fish oil supplements--one or two grams a day. If you are a vegetarian, flax seed is high in Omega-3, but it is a kind that your body has to convert to be useful. Some people's bodies do this better than others'.

For breast cancer, the question of drinking red wine, which is another component of the "Mediterranean Diet," is controversial. At least one researcher thinks it's fine to have one glass a day with a meal of the "right" foods. The consensus, however, seems to be to the contrary.

One "flat belly" diet program based on the Mediterranean diet says to eat monounsaturated fatty acids with each meal. Sources include olives, dark chocolate, olive oil, avocado, cashew, sesame, and other nuts. But fats are very nutrient dense, and as the opening sentence stated, we evolved on a less dense, lower-fat diet than we typically eat now.
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Amy
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4/19/11 Diagnosed invasive ductal carcinoma in left breast; 2.3 cm tumor, 1 axillary lymph node, weakly ER+, HER2+++
4/29/11 CT scan shows suspicious lesions on liver and lungs
5/17/11 liver biopsy
5/24/11 liver met confirmed--Stage IV at diagnosis
5/27/11 Begin weekly Taxol & Herceptin for 3 months (standard of care at the time of my DX)
7/18/11 Switch to weekly Abraxane & Herceptin due to Taxol allergy
8/29/11 CT scan shows no new lesions & old lesions shrinking
9/27/11 Finish Abraxane. Start Herceptin every 3 weeks. Begin taking Arimidex
10/17/11--Brain MRI--No Brain mets
12/5/11 PET scan--Almost NED
5/15/12 PET scan shows progression-breast/chest/spine (one vertebra)
5/22/12 Stop taking Arimidex; stay on Herceptin
6/11/12 Started Tykerb and Herceptin on clinical trial (w/no chemo)
9/24/12 CT scan--No new mets. Everything stable.
3/11/13 CT Scan--two small new possible mets and odd looking area in left lung getting larger.
4/2/13--Biopsy of suspicious area in lower left lung. Mets to lung confirmed.
4/30/13 Begin Kadcyla/TDM-1
8/16/13 PET scan "mixed," with some areas of increased uptake, but also some definite improvement, so I'll stay on TDM-1/Kadcyla.
11/11/13 Finally get hormone receptor results from lung biopsy of 4/2/13. My cancer is no longer ER positive.
11/13/13 PET scan mixed results again. We're calling it "stable." Problems breathing on exertion.
2/18/14 PET scan shows a new lesion and newly active lymph node in chest, other progression. Bye bye TDM-1.
2/28/14 Begin Herceptin/Perjeta every 3 weeks.
6/8/14 PET "mixed," with no new lesions, and everything but lower lungs improving. My breathing is better.
8/18/14 PET "mixed" again. Upper lungs & one spine met stable, lower lungs less FDG avid, original tumor more avid, one lymph node in mediastinum more avid.
9/1/14 Begin taking Xeloda one week on, one week off. Will also stay on Herceptin and Perjeta every three weeks.
12/11/14 PET Scan--no new lesions, and everything looks better than it did.
3/20/15 PET Scan--no new lesions, but lower lung lesions larger and a bit more avid.
4/13/15 Increasing Xeloda dose to 10 days on, one week off.
7/1/15 Scan "mixed" again, but suggests continuing progression. Stop Xeloda. Substitute Abraxane every 3 weeks starting 7/13.
10/28/15 PET scan shows dramatic improvement everywhere. All lesions except lower lungs have resolved; lower lungs noticeably improved.
12/18/15 Last Abraxane. Continue on Herceptin and Perjeta alone beginning 1/8/16.
1/27/16 PET scan shows cancer is stable.
5/11/16 PET scan shows uptake in some areas that were resolved on the last two scans.
6/3/16 Begin Kadcyla and Tykerb combination
6/5 - 6/23 Horrible diarrhea from K&T together. Got pneumonia.
7/15/16 Begin Kadcyla only every 3 weeks.
9/6/16 Begin radiation therapy on right lung lesion that caused the pneumonia.
10/3/16 Last of 12 radiation treatments to right lung.
11/4/16 Huffing and puffing, low O2, high heart rate, on tiniest bit of exertion. Diagnosed as radiation pneumonitis. Treated with Prednisone.
11/11/16 PET scan shows significant improvement to radiated part of right lung BUT a bunch of new lung lesions, and the bone met is getting worse.
11/22/16 Begin Eribulin and Herceptin. H every 3 weeks. E two weeks on, one week off.
3/6/17 Scan shows progression in lungs. Bone met a little better.
3/23/17 Lung biopsy. Tumor sampled is ER-, PR+ (5%), HER2+++. Getting Herceptin and Perjeta as a maintenance treatment.
5/31/17 Port placement
6/1/17 Start Navelbine & Tykerb
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