HER2 Support Group Forums - View Single Post - Finally

Mandamoo · 12-22-2011, 10:58 PM

Hi Steph - she comes from a beautiful part of our country then.
Yes - I am still on the Bolero trial - I have not really seen any reduction but I have now had 6 months of stable. I have had a partial response in my axilla node 21-13mm but not one of my lung mets has gone (they are small) or really changed. My skin met has also changed dramatically in appearance but it is still there and a little smaller. My onc has said if I hadn't had the positive biopsy on my skin she would wonder whether what the scans are showing in my lungs was actually cancer but given I had clear scans prior to my surgery in February and I am an otherwise healthy 39year old women there is little else to explain it. I tolerate the treatment very well now my dosage has been sorted and we think I am receiving the Everolimus so I hope to continue for quite some time yet.
The thinking behind the vaccine is just so appealing to me. Was there any talk about vaccines at San Antonio?
Amanda

12-22-2011, 10:58 PM	#51
Mandamoo Senior Member Join Date: Jul 2011 Location: Melbourne, Australia Posts: 432	Re: Finally - a Vaccine Trial for me! Hi Steph - she comes from a beautiful part of our country then. Yes - I am still on the Bolero trial - I have not really seen any reduction but I have now had 6 months of stable. I have had a partial response in my axilla node 21-13mm but not one of my lung mets has gone (they are small) or really changed. My skin met has also changed dramatically in appearance but it is still there and a little smaller. My onc has said if I hadn't had the positive biopsy on my skin she would wonder whether what the scans are showing in my lungs was actually cancer but given I had clear scans prior to my surgery in February and I am an otherwise healthy 39year old women there is little else to explain it. I tolerate the treatment very well now my dosage has been sorted and we think I am receiving the Everolimus so I hope to continue for quite some time yet. The thinking behind the vaccine is just so appealing to me. Was there any talk about vaccines at San Antonio? Amanda __________________ Amanda xx 40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11 Wife to my wonderfully supportive husband of 17 years! 22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old (L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins. Fec3, Taxotere and herceptin2 - stopped due to secondary diagnosis June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy! September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing. January 2013 - herceptin, carboplatin and Perjeta (compassionate access) April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.