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Old 08-16-2011, 04:08 PM   #1
ginnyg898
Senior Member
 
Join Date: Sep 2010
Location: Northern California
Posts: 64
Tamoxifen not working; Arimidex/Lupron

My Onc put me on Tamoxifen about 6 weeks ago. I did alot of research (including this site!) about reactions and side effects, of which I had none. So I insisted on a metabolic test to see if it was working; I really dont see the need to be on a med for 5 years if it is doing me no good. Well, today I got the results and I was right; my body doesnt metabolize the Tamoxifen. So my Onc suggested we do Lupron shots each three months and Arimidex. I will have my first dose later this week.

I would love to hear from those of you that have done Lupron and Arimidex; any side effects I should know of? How did you feel while on the drugs? I read about possible joint pain, not a big deal as I have that from Herceptin already anyway
__________________
41 Years Old
Dx w/IDC in August '10
No family history
ER+/PR-/HER2+
2.2cm tumor/Stage 2A
No node involvement
Tested negative for BRCA 1/2
Participated in a UCLA clinical trial testing TCH and/or Lapatinib in stage 1/2/3 bc patients that can be removed by surgery.
Underwent neo-adjuvant therapy to shrink tumor prior to surgery.
1st Surgery date: 2/16/11
Pathology report indicated ADH/DCIS in margin.
2nd Surgery: 3/21/11
Clean margins!
Started radiation: 4/11/11
Completed radiation: 7/8/11
1st post-surgical mammogram: 8/16/11 - CLEAR!
6 Weeks of Tamoxifen - Failure to Respond
Started Lupron/Arimidex: 8/29/11
Herceptin until September '11

Recurrence - August 2018
Same profile - ER+/PR-/HER2+
Undergoing neo-adjuvant therapy prior to surgery;
Gemzar, Carboplatin, Herceptin & Perjeta
Chemo through the end of 2018...
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