Wow! That could make a lot of patients err..happy. I know valproic acid, another mood mgt drug/anti-epileptic is supposed to be helpful but...1,000%? Again..wow!
If the the mechanism isn't anything specific to Dox, this would be tremendous. Even if just for Dox, could mean a lower dose could be used for desired effect with less toxicity. And if case histories are analyzed, results shouldn't take long to confirm.
An emerging liposomal encapsulated Doxo should be less toxic to begin with. Studies have suggesetd following it 24hrs later with Zoledronate greatly enhances effect..but posibly only in ER-.
So....why haven't we heard more about this?
|