HER2 Support Group Forums - View Single Post - The traditional diet of Greece and cancer.

R.B. · 03-25-2011, 05:33 PM

pibikay

^ This may help

FADS = Fatty acid desaturase

http://en.wikipedia.org/wiki/Fatty_acid_desaturase

Jackie 07

Could the failure of dietary DHA to raise DHA in breast milk be because even with additional intake the women were still not making enough to meet the needs of the foetus / their own needs and that higher intakes than used may have raised levels in breast milk. Other papers seem to suggest that in general supplementation raises DHA in breast milk

The effects of fish oil supplementation in pregnancy on breast milk fatty acid composition over the course of lactation: a randomized controlled trial.

Dunstan JA, Mitoulas LR, Dixon G, Doherty DA, Hartmann PE, Simmer K, Prescott SL.

School of Paediatrics and Child Health, The University of Western Australia, Crawley WA 6009.
Abstract

This study evaluated the longitudinal effect of fish oil in pregnancy on breast milk fatty acid composition and infant outcomes. In a randomized, controlled trial, 98 women received 2.2 g docosahexaenoic acid (DHA) and 1.1 g eicosapentaenoic acid (EPA) or olive oil from 20 wk of gestation until delivery. Fatty acid composition in breast milk (at 3 d, 6 wk, and 6 mo) and infant erythrocyte membranes (at 1 y) were determined by gas liquid chromatography. Breast milk fatty acids were examined in relationship to growth and development. Compared with control group, breast milk from women who received fish oil had proportionally higher DHA and EPA levels at 3 d and 6 wk after delivery, but this difference was no longer apparent by 6 mo. Infant DHA status at 1 y of age was directly related to DHA levels at 3 d, 6 wk, and 6 mo postpartum (but not to antenatal supplementation). Both EPA and DHA in breast milk were positively correlated with Griffith's developmental scores including hand and eye coordination. Thus, supplementation in pregnancy was associated with increased n-3 long-chain polyunsaturated fatty acids (LCPUFAs) in breast milk, particularly in early lactation, and this was positively associated with infant DHA status at 1 y.

Thanks for posting that link I will bear the contents in mind.

03-25-2011, 05:33 PM	#343
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Re: The traditional diet of Greece and cancer. pibikay ^ This may help FADS = Fatty acid desaturase http://en.wikipedia.org/wiki/Fatty_acid_desaturase Jackie 07 Could the failure of dietary DHA to raise DHA in breast milk be because even with additional intake the women were still not making enough to meet the needs of the foetus / their own needs and that higher intakes than used may have raised levels in breast milk. Other papers seem to suggest that in general supplementation raises DHA in breast milk The effects of fish oil supplementation in pregnancy on breast milk fatty acid composition over the course of lactation: a randomized controlled trial. Dunstan JA, Mitoulas LR, Dixon G, Doherty DA, Hartmann PE, Simmer K, Prescott SL. School of Paediatrics and Child Health, The University of Western Australia, Crawley WA 6009. Abstract This study evaluated the longitudinal effect of fish oil in pregnancy on breast milk fatty acid composition and infant outcomes. In a randomized, controlled trial, 98 women received 2.2 g docosahexaenoic acid (DHA) and 1.1 g eicosapentaenoic acid (EPA) or olive oil from 20 wk of gestation until delivery. Fatty acid composition in breast milk (at 3 d, 6 wk, and 6 mo) and infant erythrocyte membranes (at 1 y) were determined by gas liquid chromatography. Breast milk fatty acids were examined in relationship to growth and development. Compared with control group, breast milk from women who received fish oil had proportionally higher DHA and EPA levels at 3 d and 6 wk after delivery, but this difference was no longer apparent by 6 mo. Infant DHA status at 1 y of age was directly related to DHA levels at 3 d, 6 wk, and 6 mo postpartum (but not to antenatal supplementation). Both EPA and DHA in breast milk were positively correlated with Griffith's developmental scores including hand and eye coordination. Thus, supplementation in pregnancy was associated with increased n-3 long-chain polyunsaturated fatty acids (LCPUFAs) in breast milk, particularly in early lactation, and this was positively associated with infant DHA status at 1 y. Thanks for posting that link I will bear the contents in mind.