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The mean diameter of tumours was 4.2 cm.
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PET-CT or/and MDCT showed complete response in 11/13 liver metastases; all bone, soft-tissue and pancreatic lesions were palliated in symptoms, with complete response to PET-CT, MDCT or magnetic resonance imaging (MRI); the liposarcoma was almost completely ablated at MRI. Local oedema was observed in three patients. No other side effects were observed. All patients were discharged 1-3 days after treatment.
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Wow! Sounds like tremendous response for larger tumors. I know my heart sank when mom was told by an interventional radiologist that success with cryo or RF ablation goes down significantly at 3cm. Too bad oncs don't seem to be aware of this....
As with most things in mets land, earlier the better.
The question will be whether anyone will do this level of HIFU outsode trials..especially in the US.
The immune response issue is a good question. It seems like ablation can trigger good and not so good immune reactions.