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Old 12-17-2010, 03:55 PM   #4
Becky
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Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
Re: Liver Mets: What Does 60% Progesterone Positive Mean

Like estrogen, I believe that Tamoxifen or an AI might be of assistance however, if I were you, I would have my pathology slides sent to a large research cancer center (MD Anderson, Johns Hopkins, Sloan Kettering, Fox Chase etc) and have them redo the pathology. The reason I am suggesting a second opinion is that being moderate/high on progesterone only is a very odd thing. Quite rare in fact and if I were you, I would want to know that the estrogen receptor isn't involved too because that insures the anti hormonals will really work. Just my two cents. Having a positive estrogen receptor and a negative progesterone receptor is rare too but much more common than vice versa like yours.

Are you premenopausal? If so, an oophorectomy may be helpful. Talk to your oncologist.
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Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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