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Old 11-30-2010, 10:12 AM   #15
TanyaRD
Senior Member
 
Join Date: Sep 2009
Posts: 358
Re: Herceptin and supplements

Sorry to come in late on this conversation. I usually stay in the "Diet and Nutrition" section only but would like to comment on this thread.

Generally speaking, the chemotherapy/cancer treatment agents we are most careful with in regards to antioxidants are those that produce free radicals. I am pasting a chart below.

Table 1: Chemotherapeutic Agents Producing Free Radicals
  • Alkylating agents
    cisplatin (Platinol®)
    carboplarin (Paraplatin®)
    chlorambucil (Leukeran®)
    carmustine (BiCNU®)
    cyclophosphamide (Cytoxan®)
    busulfan (Myleran®)
    ifosfamide (Ifex®)
  • Anthracyclines
    doxorubicin (Adriamycin®, Doxil®)
    daunorubicin (Cerubidine®)
    epirubicin (Ellence®)
    Mitomycin (Mutamycin®)
    BIeomycin (Bleoxane®)
  • Podophyllum agents
    etoposide(VP-I6, Vespid®)
    teniposide (Vumon®)
Some evidence demonstrates that high dose antioxidants (amount in diet is usually much lower and safe with treatment) may make treatment less effective.

Herceptin does not fall into these categories. I am generally cautious with my patients and recommend they get their antioxidants from food. I often recommend an Omega-3 supplement, calcium and vitamin D which all appear safe in combination with Herceptin.

Hope this is helpful.

Tanya
(Registered Dietitian)
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