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Re: Zometa
I do not have bone mets and hope never to have them. My onc, when he suggested Zometa quoted the current research and I cannot quite remember it. Something like 1000 premenopausal women were studied and the number of bone mets they experienced in that group was reduced by I believe 30%. Perhaps some of the more savy women on here will have more exact data for you. I have also read about the other pathways that Her2 can use and that Zometa is one of those blocks. They are also suggesting that to prevent bone mets Zometa should be given in smaller doses more frequently and that is a question I have for my onc on Monday as I am being given the standard treatment of once every 6 months. It is an infusion of about 15 minutes and the first time I had a reaction similar to my experience to the chemo drug, Taxol but the subsequent infusions were without reaction. Search Zometa on this site and see what others have said. Many of us are on it. Best wishes.
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12/17/08 biopsy after two 6 mos mammo recalls
12/30/08 diagnosed high grade IDC & DCIS ER/PR +, Her2 (+++) post menopausal/age 57
1/15/09 double mastectomy/skin sparing; no evidence of vascular/lymphatic invasion, 8neg/8 nodes (tumor 8.0mm)
2/16/09 given portacath/removed 4/30/10
2/18/09 "surprise" 2.0mm tumor/positive borders~completed 28 rads 10/09.
2/23/09 until 4/19/10~treatments every 3wks (4 Cytoxan + Adriamycin, 4 Taxol + Herceptin, 13 Herceptin alone)
8/09 osteoporosis diagnosis/Zometa 3 yrs of 1x/6 months
Chemo side effects; Deafness, kidney function loss
11/09 began Aromatase Inhibitor (Femara)/Feb2014, stopped Femara early/after 3 mos began Tamoxifen for 8 mos to complete 5 years
11/10 Reconstruction, directly to silicone implants
12/11 nipples by skin graft/Right breast size reduced
I have heard there are troubles of more than one kind
Some come from ahead and some come from behind.
But I've bought a big bat. I'm all ready you see.
Now my troubles are going to have trouble with me!
Dr. Seuss
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